Epigenetic regulation of Ucp1 by trandcription factor Etv4
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243845
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We found a far regualtory element on Ucp1 genome locus at -12kb region which was drasticlly regulated by transcription factor Etv4. ATAC-seq and H3K27ac, H3K27me3, CTCF cut&run was performed in BAT and iWAT tissue. ATAC-seq of -12kb enhancer repression by CRISPRi and knocking down Etv4 was performed in BAT cell line. RNA-seq of Etv4 knockdown was performed
创建时间:
2025-07-10



