Activity analysis of MS-0022 chemotype (See structure in figure 1B).
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Biological activity of side group analogues of MS-0022 measured by pathway inhibition in Shh induced Shh-L2 cells and by BODIPY-cyclopamine competition, including cLogP (computed LogP, octanol/water partition coefficient) and polar surface area (PSA).
创建时间：
2015-12-02
