Efficacy of Topical Spironolactone in Acne Vulgaris: A Meta-Analysis of Randomized Trials

This dataset includes supplementary materials supporting the Brief Report submitted to the Journal of the American Academy of Dermatology (JAAD) titled “Efficacy of Topical Spironolactone in Acne Vulgaris: A Meta-Analysis of Randomized Trials.”

The dataset contains:

Subgroup forest plot comparing gel vs cream formulations (Figure 2)
Overall forest plot comparing topical spironolactone vs placebo (Figure 1)
PRISMA 2020 checklist outlining the study selection process
Risk of bias assessment table (ROB)[figures and sheet]
Data extraction table summarizing study characteristics and outcomes
Full reference list (beyond the 5 cited in the main brief report)
Prisma Flowchart

These files provide transparency and reproducibility of the meta-analysis findings and allow readers and reviewers to explore detailed methodology, study comparisons, and quality assessments that could not be included in the main manuscript due to space limitations.

All included materials align with PRISMA 2020 and ICMJE guidelines.