Effects of Dabigatran and Rivaroxaban on TG in PRP in the presence and absence of Aspirin and AR-C66096.

TG, thrombin generation triggered by 1 pM recombinant tissue factor; PRP, platelet-rich plasma; Asp, aspirin 100 µM; AR-C66096, 1 µM; Dabi, dabigatran; Riva, rivaroxaban; LT, lag time; TTP, time to peak of TG; PH, peak height of TG; ETP, endogenous thrombin generation potential.
Data are shown as the mean ± SD. *P<0.05, **P<0.01, and ***P<0.001 vs. Asp+AR-C.
§indicates that, since TG curves did not come down to the baseline within 120 min, ETP values were calculated by setting the start tail at 120min.