p53 dimers elicit unique tumor suppressive activities through an altered metabolic program

NIAID Data Ecosystem2026-03-14 收录

肿瘤代谢调控

p53蛋白功能

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE220966 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-03-04

Gene Expression Profile In Presence of p53 alone, p47 alone, or both

基因表达调控

p53蛋白功能

H1299 cells (p53-/-) were transfected with plasmid constructs expressing p53 alone, p47 alone or both, and gene expression profile was probed Agilent one-color experiment,Organism: Homo sapiens, Agile

NIAID Data Ecosystem50

Metabolic Reprogramming of Terminally Exhausted CD8+ T-cells by Interleukin-10 Enhances Anti-Tumour Immunity

肿瘤代谢调控

T细胞功能重编程

Terminally exhausted CD8+ T-cells, which hold certain level of anti-tumour cytotoxicity but largely reduced proliferation capacity, contribute directly to tumour growth control. However, this subpopul

NIAID Data Ecosystem30

A regulatory axis of YY1-PFKP promotes aggressive prostate tumorigenesis via potentiating tumor cell metabolism [RNA-seq]. A regulatory axis of YY1-PFKP promotes aggressive prostate tumorigenesis via potentiating tumor cell metabolism [RNA-seq]

前列腺癌分子机制

肿瘤代谢调控

Yin Yang 1 (YY1) acts as a transcription factor crucially involved in cell proliferation, differentiation and survival. We here report that YY1, through gene expression regulation, plays an important

NIAID Data Ecosystem20

ACLY and ACC1 Regulate Hypoxia-Induced Apoptosis by Modulating ETV4 via α-ketoglutarate

肿瘤代谢调控

缺氧病理机制

In order to propagate a solid tumor, cancer cells must adapt to and survive under various tumor microenvironment (TME) stresses, such as hypoxia or lactic acidosis. To systematically identify genes th

NIAID Data Ecosystem40

PPARδ Activation Acts Cooperatively with 3-Phosphoinositide-Dependent Protein Kinase-1 to Enhance Mammary Tumorigenesis

肿瘤代谢调控

乳腺肿瘤信号通路

Peroxisome proliferator-activated receptorδ (PPARδ) is a transcription factor that is associated with metabolic gene regulation and inflammation. It has been implicated in tumor promotion and in the r

NIAID Data Ecosystem30

p53 dimers elicit unique tumor suppressive activities through an altered metabolic program

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