MitoKO: A library of base editors for precise ablation of all protein-coding genes in the mouse mitochondrial genome
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP374547
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资源简介：
We design and apply a highly optimized library of double-stranded DNA deaminase (DddA)-derived cytosine base editors (DdCBEs) - MitoKO - to precisely ablate every mtDNA protein coding gene in the mouse mitochondrial genome Overall design: Base editing of citosine to timine to introduce premature STOP codons in protein-encoding genes of the mouse mtDNA
创建时间：
2023-05-25
