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Intrahepatic Microbes Govern Liver Immunity

NIAID Data Ecosystem2026-03-13 收录

器官免疫微环境

微生物-免疫互作

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https://www.ncbi.nlm.nih.gov/sra/SRP341082 数据链接链接失效反馈

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Liver harbors a distinct microbiome that regulates hepatic immune function by programming NKT cells

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创建时间：

2021-11-29

先天免疫调控

器官免疫微环境

Lambda interferons (IFN-λs) are a major component of the innate immune defense to viruses, bacteria and fungi. In human liver, IFN-λ not only drives antiviral responses, but also promotes inflammation

Research Data Australia60

HBM374.DMXZ.352

空间蛋白质组学

器官免疫微环境

CODEX data from the thymus of a 21-year-old black or african american female

NIAID Data Ecosystem40

Broad-spectrum antibiotics disrupt homeostatic efferocytosis

免疫稳态调节

微生物-免疫互作

The clearance of apoptotic cells, termed efferocytosis, is essential for tissue homeostasis and prevention of autoimmunity. Although past studies have elucidated local molecular signals that regulate

NIAID Data Ecosystem30

Unveiling the heterogeneity of NKT cells in the liver through single cell RNA sequencing

免疫细胞亚型功能分析

器官免疫微环境

CD1d-dependent type I NKT cells, which are activated by lipid antigen, are known to play important roles in innate and adaptive immunity, as are a portion of type II NKT cells. However, the heterogene

NIAID Data Ecosystem50

Single cell transcriptomic analysis of thymic epithelial cells. Mus musculus

单细胞转录组学

器官免疫微环境

Single cell transcriptomic analysis of wildtype and AireKO thymic epithelial cells Overall design: Single cells were sorted by FACS for single cell RNAseq library preparation

NIAID Data Ecosystem30

Intrahepatic Microbes Govern Liver Immunity

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