Chemical modification by peroxynitrite enhances TLR4 activation of the grass pollen allergen Phl p 5

In this study, we investigate how the physiological reagent peroxynitrite (ONOO– ) can change TLR4 activation of the grass pollen allergen Phl p 5 through protein nitration and the formation of protein dimers and higher oligomers.

本研究旨在探讨生理活性试剂过氧亚硝酸盐（ONOO-）如何通过蛋白质硝化作用以及蛋白质二聚体和更高聚体的形成，改变草粉致敏原Phl p 5的TLR4激活作用。