How specific cells respond to signaling pathways is largely encoded in the DNA sequence. However, the sequence rules result from complex interactions between signaling and cell-type-specific transcrip
The Hippo pathway, by tightly controlling the phosphorylation state and activity of the transcription cofactors YAP and TAZ is essential during development and tissue homeostasis whereas its deregulat
aEvaluated by densitometry of PAGE Gels Stained with Coomassie Blue R-250 bPurified according to cGMP standards ND = not done WT = wild type CH = codon harmonized