<strong>Supplemental Table 3</strong>

<strong>Supplemental Table 3. Metabolome comparison among different treatment groups. </strong>Fold change (FC) analysis is to compare the absolute values of change between group means in <strong>A</strong>) lumen and <strong>B</strong>) serum. Original metabolite measurement without normalization in FC analysis. Two-sample t-test to calculate significance value. Metabolites with p value &lt;0.05 included in the table. Pathway enrichment analysis to indicate the significantly affected pathways by treatment in <strong>C</strong>) lumen and <strong>D</strong>) serum. Enrichment analysis using predefined libraries of metabolites using metabolite set enrichment analyses (MSEA) (Xia and Wishart, 2010).