PDGFRb+ Mesenchymal Cells, but Not NG2+ Mural Cells, Contribute to Cardiac Fat

we performed lineage tracing studies using various genetic models, and found that cardiac mesenchymal cells (MCs) contribute to CAs in postnatal development and adult homeostasis. we found that PDGFRb+ cells are heterogenous, and demonstrate that PDGFRb+ MCs, but not NG2+ coronary vascular mural cells, are the major source of intramyocardial. we performed single cell RNA sequencing to compare the heterogeneity.