Crystal Structure of rat protein farnesyltransferase complexed with a bezoruran inhibitor and FPP
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Crystal Structure of rat protein farnesyltransferase complexed with a bezoruran inhibitor and FPP Descriptor: 3-{2-[(S)-(4-cyanophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-5-nitro-1-benzofuran-7-yl}benzonitrile, ACETIC ACID, FARNESYL DIPHOSPHATE, ... Authors: Fukami, T.A, Sogabe, S, Nagata, Y, Kondoh, O, Ishii, N. Deposit date: 2008-02-22 Release date: 2009-02-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Synthesis and structure-activity relationships of novel benzofuran farnesyltransferase inhibitors Bioorg.Med.Chem.Lett., 19, 2009
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2008-02-22
