Crystal structure of Bcl-xL in complex with a small molecule inhibitor
收藏Protein Data Bank Japan2024-11-20 更新2026-06-30 收录
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Crystal structure of Bcl-xL in complex with a small molecule inhibitor Descriptor: (3M)-3-(1-{[(1r,3R,5S,7r)-adamantan-1-yl]methyl}-5-methyl-1H-pyrazol-4-yl)-6-{8-[(1,3-benzothiazol-2-yl)carbamoyl]-3,4-dihydroisoquinolin-2(1H)-yl}pyridine-2-carboxylic acid, Bcl-2-like protein 1, CADMIUM ION Authors: Judge, R.A, Judd, A.S. Deposit date: 2024-02-22 Release date: 2024-10-16 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.961 Å) Cite: BCL-X L -targeting antibody-drug conjugates are active in preclinical models and mitigate on-mechanism toxicity of small-molecule inhibitors. Sci Adv, 10, 2024
创建时间：
2024-02-22
