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Non-receptor Protein Tyrosine Phosphatase SHP2 F285S in Complex with Allosteric Inhibitor JLR-2

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6bn5
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Non-receptor Protein Tyrosine Phosphatase SHP2 F285S in Complex with Allosteric Inhibitor JLR-2 Descriptor: 3-benzyl-8-chloro-2-hydroxy-4H-pyrimido[2,1-b][1,3]benzothiazol-4-one, Tyrosine-protein phosphatase non-receptor type 11 Authors: Blacklow, S.C, Stams, T, Fodor, M, LaRochelle, J.R. Deposit date: 2017-11-16 Release date: 2017-12-13 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2. Bioorg. Med. Chem., 25, 2017
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2017-11-16
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