Transportability of Adolescent Sexual Risk Prevention Interventions, United States, 2000-2015

The cost and challenge of running clinical trials in each subpopulation and each setting results in a patchwork of evidence. Often, some interventions are evaluated with trial samples that are distinct in the distribution of potential treatment modifiers. These gaps in understanding can be filled using transportability methods where the subset of trials that evaluate an intervention are used to transport the potential outcome mean for that intervention to the target population. Despite this, transportability analysis suffers from systematic missing data, a missing data problem that is unique to the settings where data comes from multiple sources.
This harmonized dataset was created to evaluate novel transportability methods. It includes data from six trials of adolescent sexual risk prevention. Interventions evaluated include emotion regulation, skills training, family based, and health promotion. Populations studied include adolescents in mental health care (aged 13-18), those in alternative educational placement (aged 12-19), those indicated by school personnel as having mental or behavioral health issues (aged 12-14), and Black and African American adolescents (aged 14-17) that had lived in the urban areas of four major U.S. cities.