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CRYSTAL STRUCTURE OF KRAS G12D (GPPCP) IN COMPLEX WITH BI 2852

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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CRYSTAL STRUCTURE OF KRAS G12D (GPPCP) IN COMPLEX WITH BI 2852 Descriptor: (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one, GTPase KRas, MAGNESIUM ION, ... Authors: Kessler, D, Mcconnell, D.M, Mantoulidis, A. Deposit date: 2018-05-16 Release date: 2019-07-31 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Drugging an undruggable pocket on KRAS. Proc.Natl.Acad.Sci.USA, 116, 2019

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2018-05-16
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