Isatin <i>N</i>,<i>N</i>′‑Cyclic Azomethine Imine 1,3-Dipole and Abnormal [3 + 2]-Cycloaddition with Maleimide in the Presence of 1,4-Diazabicyclo[2.2.2]octane

NIAID Data Ecosystem2026-03-10 收录

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https://figshare.com/articles/dataset/Isatin_i_N_i_i_N_i_Cyclic_Azomethine_Imine_1_3-Dipole_and_Abnormal_3_2_-Cycloaddition_with_Maleimide_in_the_Presence_of_1_4-Diazabicyclo_2_2_2_octane/4578670

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资源简介：

A new isatin N,N′-cyclic azomethine imine synthon was devised, and an unexpected abnormal [3 + 2]-cycloaddition with maleimide catalyzed by 1,4-diazabicyclo[2.2.2]octane (DABCO) has been disclosed. A variety of tricyclic spiropyrrolidine oxindoles bearing a dinitrogen heterocycle and succinimide scaffold were obtained in excellent yields (up to 96%) and diastereoselectivities (up to 97:3) under mild conditions.

创建时间：

2017-01-23