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Jmjd3 is required for tissue-restricted antigens expression in mTECs

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110360
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To understand the role of Jmjd3 in medullary thymic epithelial cells (mTECs) function and development, Jmjd3 was conditionally deleted in thymic epithelial cells. At the age of 4 weeks, mTECs were sorted by flow cytometry and RNA-seq was performed to identify the genes targeted by Jmjd3 for repression. RNAseq on control or Jmjd3-deficient murine medullary thymic epithelial cells.
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2021-05-12
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