List of most frequent mtSNPs from enhanced patterns (see Figure 5) in semi-supercentenarians vs. healthy normals.

Column 2 shows the haplogroup specificity for the SNP. The next two columns show the nucleotide in rCRS and the mutation. The last two columns are for the corresponding gene and the ��sense�� of the mutation �C synonymous or nonsynonymous. SNPs shown in bold blue are the six SNPs in the top left corner of Figure 5, the ones most correlated with patterns enriched in the longevity group. Note that these are either non-specific or markers for haplogroup D4a. The locations 152 and 16129 are known mutational hotspots in the hypervariable regions HVS-II and HVS-I respectively and hence their correlation with longevity cannot be considered significant.