Phillygenin attenuates carbon tetrachloride-induced liver fibrosis via modulating inflammation and gut microbiota. mouse gut metagenome

Liver fibrosis is a chronic pathological process of abnormal hyperplasia of connective tissue in liver caused by various pathogenic factors, and its main feature is the excessive deposition of extracellular matrix. However, there are currently no drugs approved for the treatment of liver fibrosis. More importantly, the corrective effect of PHI on the imbalance of gut microbiota was confirmed by sequencing of the 16S rRNA gene.