Metagenomic samples, functional modules, and metabolic pathways analyzed here and differentially abundant in the human microbiome.

649 total microbiome samples spanning seven body habitats were reconstructed into 232 small functional modules and 297 large pathways using HUMAnN. Differential abundance (over- or under-enrichment) in at least one body site was tested using LEfSe [23] and differential coverage by a minimum prevalence (90% for modules, 50% for pathways) threshold.