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Crystal structure of BTK C481S kinase domain in complex with pirtobrutinib

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Protein Data Bank Japan2023-10-25 更新2026-05-23 收录
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Crystal structure of BTK C481S kinase domain in complex with pirtobrutinib Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SULFATE ION, ... Authors: Cedervall, E.P, Morales, T.H, Allerston, C.K. Deposit date: 2022-12-21 Release date: 2023-03-01 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.334 Å) Cite: Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor. Blood, 142, 2023

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2022-12-21
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