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Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons

ChEBI2016-07-01 更新2026-07-12 收录

干细胞衍生神经元

神经-心脏组织互作

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-80689 数据链接链接失效反馈

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Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons

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创建时间：

2016-07-01

神经疾病建模

干细胞衍生神经元

16p13.11 copy number variants (CNVs) have been associated with autism, schizophrenia, psychosis, intellectual disability, and epilepsy. The majority of 16p13.11 deletions or duplications occur within

NIAID Data Ecosystem50

Data files Electrical maturation of neurons derived from human embryonic stem cells

干细胞衍生神经元

神经电生理学

Dataset 1: Additional images of raw microscopy showing neurons derived from hESCs in bright field and stained, as well as original images for a single hESC colony (corresponding to Figure 1B-C). Datas

Figshare2014-08-25 更新50

Gene expression data from induced Pluripotent Stem cells from Parkinson's Disease patients harboring mutations in the GBA1 gene, and from healthy control donors

帕金森病疾病建模

干细胞衍生神经元

We have generated human induced Pluripotent Stem cells (hiPSc) using Retroviral and Sendai virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess ch

NIAID Data Ecosystem20

Protein aggregation and calcium dysregulation are the earliest hallmarks of familial Parkinson’s disease in human midbrain dopaminergic neurons

家族性帕金森病早期病理

干细胞衍生神经元

Mutations in the SNCA gene cause autosomal dominant Parkinson’s disease (PD), with progressive loss of dopaminergic neurons in the substantia nigra, and accumulation of aggregates of α-synuclein. Howe

NIAID Data Ecosystem50

RNAseq analysis of DPSC-derived neurons from Neurotypical control, ROHHAD, and CCHS subjects. RNAseq analysis of DPSC-derived neurons from Neurotypical control, ROHHAD, and CCHS subjects

罕见神经遗传疾病转录组学

干细胞衍生神经元

A major challenge to the study and treatment of neurogenetic syndromes is the difficulty in gaining access to live neurons from individuals with these disorders. Although other sources of stem cells a

NIAID Data Ecosystem30

Functional Connection with Cardiac Tissues Confers Maturation Phenotypes in hPSC-Derived PHOX2B::GFP Expressing Sympathetic Neurons

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