Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved signaling mechanism
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE124388
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Purpose: The goal of this study is to analyze the Cryptochrome-Cop1 axis in mammals Methods: mouse embryonic fibroblasts treated with dexamethasone, KL001 and/or Cop1 knockdown. Results: The transcriptomic analysis helps us to support our finding that the Cryptochromes-dependent repression of the glucocorticoid receptor is mediated by Cop1. All samples generated by deep sequencing in triplicate
创建时间：
2019-08-01
