Crystal structure of the kinase domain of Bruton's Tyrosine kinase with GDC0834
收藏Protein Data Bank Japan2023-12-06 更新2026-03-21 收录
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Crystal structure of the kinase domain of Bruton's Tyrosine kinase with GDC0834 Descriptor: N-{3-[6-({4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]phenyl}amino)-4-methyl-5-oxo-4,5-dihydropyrazin-2-yl]-2-methylphenyl }-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide, SULFATE ION, Tyrosine-protein kinase BTK Authors: Hymowitz, S.G, Maurer, B. Deposit date: 2014-02-13 Release date: 2015-01-28 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2014-02-13
