Expression data of the endothelial-to-hematopoietic transition in E8.5 concepti

ChEBI2013-11-11 更新2026-07-21 收录

胚胎造血发育

内皮-造血转化

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Expression data of the endothelial-to-hematopoietic transition in E8.5 concepti

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2013-11-11

De novo generation of macrophage from placenta-derived hemogenic endothelium

胚胎造血发育

单细胞转录组学

We profile the transcriptional landscape of mouse fetal placenta and identify four distinct types of haematopoietic stem/progenitor cells (HSPCs) during mid-gestation using single-cell RNA sequencing.

NIAID Data Ecosystem70

Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression [CITE-seq]. Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression [CITE-seq]

造血干细胞

内皮-造血转化

Hematopoietic stem and progenitor cells (HSPCs) originate from an endothelial-to-hematopoietic transition (EHT) during embryogenesis. Characterization of early hemogenic endothelial (HE) cells is requ

NIAID Data Ecosystem50

A Sox17 downstream gene Rasip1 is involved in the hematopoietic activity of intra-aortic hematopoietic clusters in the midgestation mouse embryo. Mus musculus

胚胎造血发育

造血干细胞调控

Background: During mouse embryonic development, definitive hematopoiesis is first detected around embryonic day (E) 10.5 in the aorta-gonad-mesonephros (AGM) region. Hematopoietic stem cells (HSCs) ar

NIAID Data Ecosystem20

RUNX1 and the endothelial origin of blood

胚胎造血发育

生血内皮细胞转录组

The transcription factor RUNX1 is required in the embryo for formation of the adult hematopoietic system. Here we describe the seminal findings that led to the discovery of RUNX1 and of its critical r

NIAID Data Ecosystem60

RNA-Seq of sorted E10.5 and E11.5 AGM cell populations from Gata3-GFP embryos

胚胎造血发育

单细胞转录组学

The aim of this study was to examine the whole transcriptome of pools of 20 cells of Gata3-expressing AGM subpopulations (haematopoietic [HC], mesenchymal [MC], sympathetic nervous system [SNS], and e

NIAID Data Ecosystem20

Expression data of the endothelial-to-hematopoietic transition in E8.5 concepti

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