Enriched molecular function/cellular component Gene Ontology (GO) categories for the lists of differentially expressed transcripts in spleen leukocytes from 2 week and 4 week old NOD mice compared to two control strains.

One-way ANOVA (p<0.05, Benjamini-Hochberg) of mRNA expression data followed by hierarchical clustering identified 187 and 327 probe sets whose expression was altered in spleen leukocytes from NOD mice compared to two control strains (NON and C57BL/6) at 2 weeks and 4 weeks, respectively. The lists of differentially expressed genes were analyzed in WebGestalt (http://bioinfo.vanderbilt.edu/webgestalt) for enriched GO categories using hypergeometric test (p<0.01, Benjamini-Hochberg); dashes (-) indicate that the corresponding categories were not significantly enriched at the respective ages. Categories represented by ≥5 genes are shown. Bold text indicates categories that were common to both age groups.