Colorado potato beetle transcriptional response to aegerolysin treatment. Colorado potato beetle transcriptional response to aegerolysin treatment

Protein complexes of aegerolysins pleurotolysin A2 (PlyA2) and pleurotolysin B (PlyB) from oyster mushrooms Pleurotus sp. display targeted toxicity against Colorado potato beetle (CPB; Leptinotarsa decemlineata) larvae. This selective toxicity is achieved through aegerolysins' interaction with insect-specific membrane sphingolipids. This study explores the potential adaptive response of CPB larvae to the aegerolysin complex. Overall design: Leptinotarsa decemlineata larvae fed on potato leaves soaked in PlyA2/PlyB/buffer solution vs control larvae fed on leaves soaked in buffer; two sampling time points - 1 and 5 days post treatment