Association of selected UBC susceptibility variants with NMIBC recurrence and progression by smoking status.

CNV: copy number variant; del. = deletion; C.E.: converging error; HR: hazard ratio; CI: confidence intervalaPresented effect estimates and statistical significance are based on multivariable Cox proportional hazard regression analyses with adjustment for treatment (TURT + both adjuvant i.v. CT and IT vs. TURT + adjuvant i.v. IT vs. TURT + adjuvant i.v. CT vs. TURT only (± one direct p.o. i.v. CT instillation));brs1495741: tag SNP for NAT2 acetylation status (GG = rapid, AG = intermediate, AA = slow);cbased on exploratory analysis