Gene Expression Signature of Microcalcification among Taiwanese Breast Cancer. Gene Expression Signature of Microcalcification among Taiwanese Breast Cancer

Microcalcification is one of the most common radiological and pathological features of breast ductal carcinoma in situ (DCIS), and to a lesser extent, invasive ductal carcinoma. We evaluated transcriptional profiles associated with ectopic mammary mineralization. We evaluated the transcriptional profiles associated with breast cancer microcalcification for Taiwanese breast cancer and a gene expression signature was derived. Overall design: A total of 109 consecutive breast cancers were assayed with microarrays. The associations of differentially expressed genes with microcalcifications and relevant clinical features were evaluated.