The siRNA seed region is divided into two functionally different domains in RNA interference in response to 2´-OMe modifications
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE188314
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资源简介：
To investigate effects of siRNA with 2'-O-methyl (2'-Ome) modifications on genome-wide off-targetat, we analyzed gene expression profile of HeLa cells transfected by their siRNAs. Total RNAs were extracted from HeLa cells transfected by unmodified or 2'-O-methyl (2'-Ome) modified siRNA and performed microarray analysis.
创建时间：
2022-01-13
