Crystal structure of human ALDH1A1 bound to compound (R)-28
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of human ALDH1A1 bound to compound (R)-28 Descriptor: 5-{4-[(Z)-2-hydroxyethenyl]phenyl}-1-methyl-6-{[(1R)-1-phenylethyl]sulfanyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, CHLORIDE ION, Retinal dehydrogenase 1, ... Authors: Hurley, T.D, Buchman, C. Deposit date: 2020-08-26 Release date: 2020-12-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy. Eur.J.Med.Chem., 211, 2020
创建时间：
2020-08-26
