Gut Microbiome Profile in Symptomatic Patients with or without Lumbar Degenerative Spondylolisthesis. Human Feces Metagenome

Lumbar degenerative spondylolisthesis (LDS), characterized as degeneration of the intervertebral disc and structural changes of the facet joints, is a condition with varying degrees of instability that may lead to pain, canal stenosis, and subsequent surgical intervention. However, the etiology of LDS remains inconclusive. Dysregulation of the gut microbiome may stimulate systemic inflammation and has been associated with various human conditions. The implications of gut microbiome dysbiosis upon spine health is a very novel field and in its infancy. The following study aimed to assess the presence of gut microbiome dysbiosis in symptomatic patients with or without LDS