Additional file 9 of Bone marrow infiltrated natural killer cells predicted the anti-leukemia activity of MCL1 or BCL2 inhibitors in acute myeloid leukemia
Targeting the MYST acetyltransferases are an exciting therapeutic opportunity in acute myeloid leukaemia (AML). Here we define the individual and combined contribution of KAT6A, KAT6B and KAT7, in ran
BackgroundImmunogenic cell death (ICD) has been categorized as a variant of regulated cell death that is capable of inducing an adaptive immune response. A growing body of evidence has indicated that
Normalised gene expression counts (tpm) for 13 pre-treatment tumour biopsy samples collected from patients with early stage HER2+ breast cancer who subsequently received anti-HER2 and chemotherapy neo
Although there are many prospective targets in the tumor microenvironment (TME) of high-grade serous ovarian cancer (HGSOC), pre-clinical testing is challenging especially as there is limited informat
BackgroundPolyamine metabolism is closely associated with tumorigenesis, progression, and the tumor microenvironment (TME). This study aimed to determine whether polyamine metabolism-related genes (PM
