TFs which are significantly enriched for multiple binding sites per operon, compared to the random promoter architecture model.

The p-value for data in RegulonDB 8.5 is given by the probability of an equal or more extreme outcome in the random promoter architecture model. The particular example of OxyR regulating the fhuF at four binding sites is shown in Fig. 5. An extended version of Table 2, covering 115 TFs, is available in S2 Table.TFs which are significantly enriched for multiple binding sites per operon, compared to the random promoter architecture model.