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Elicitation and Affinity Maturation of VRC01-Class Broadly Neutralizing Antibodies in a Human Antibody Gene Knock in Mouse Model. Mus musculus

NIAID Data Ecosystem2026-03-11 收录

黏膜疫苗免疫策略

广谱中和抗体

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA623583 数据链接链接失效反馈

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We test sequential immunization strategies in the VH1-2/LC transgenic mice to elicit VRC01-class bnAbs.

应用场景：

创建时间：

2020-04-07

黏膜疫苗免疫策略

结核疫苗开发

Understanding the in vivo fate of vaccine antigens and adjuvants and their safety is crucial for the rational design of mucosal subunit vaccines. Prime and pull vaccination using the T helper 17-induc

NIAID Data Ecosystem110

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34

冠状病毒结构

广谱中和抗体

SARS-CoV-2 Spike protein in complex with a pan-sarbecovirus nanobody 2-34 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-

Protein Data Bank Japan2024-10-23 更新40

Vaccination regimens.

黏膜疫苗免疫策略

临床前剂量研究

*Quantities indicate the amounts of immunogen or adjuvant delivered to each mouse in the indicated group. S = soluble protein; E = encapsulated protein. Subscripts indicate amount of soluble or encaps

Figshare2015-12-02 更新20

Inhibitory activity of IBP-CP24 (C34 as a control) or bNAbs (NBD556 as a control) when used alone or in combination against infection HIV-1 IIIB or JR-CSF a .

抑制剂评估

广谱中和抗体

Inhibitory activity of IBP-CP24 (C34 as a control) or bNAbs (NBD556 as a control) when used alone or in combination against infection HIV-1 IIIB or JR-CSFa.

NIAID Data Ecosystem40

Identification of Non-HIV Immunogens That Bind to Germline b12 Predecessors and Prime for Elicitation of Cross-clade Neutralizing HIV-1 Antibodies

HIV疫苗免疫原设计

广谱中和抗体

A fundamental challenge for developing an effective and safe HIV-1 vaccine is to identify vaccine immunogens that can initiate and maintain immune responses leading to elicitation of broadly neutraliz

Figshare2016-01-15 更新40

Elicitation and Affinity Maturation of VRC01-Class Broadly Neutralizing Antibodies in a Human Antibody Gene Knock in Mouse Model. Mus musculus

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