BRD4 represses CBX5
收藏NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE78704
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资源简介：
BRD4 is amplified and/or up-regiulated in a subset of ovarian cancer which correlates with a poor survival siRNA sensitization screens in the presence of CHK1 inhibitor, LY2606368, identify BRD4 as a therapeutic target in ovarian cancer. BRD4 suppression by either siRNA or using JQ1 increases CBX5 expression (i) BRD4 knockdown by siBRD4 in Ovcar8, performed in 3 replicates. (ii) BRD4 inhibition using JQ1 in Ovcar8, performed in 3 replicates.
创建时间：
2019-08-02
