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The effect of spleen tyrosine kinase on bone marrow monocytes in atherosclerosis

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NIAID Data Ecosystem2026-05-01 收录
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Spleen tyrosine kinase (Syk)del/del mice suppressed atherosclerosis and Sykdeldel macrophages showed cell migration impairment. To investigate the Syk-associated genes in cell migration, we analyzed RNA-Seq of bone marrow monocytes. Bone marrow monocytes were purified from mice fed with a high-fat diet for eight weeks and compared Syk+/+Rosa26CreER(T2)+/+ and Sykdel/delRosa26CreER(T2)+/+. Each sample was in triplicate.

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2023-10-21
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