five

NGS on the 5BP correction followed by genome editing therapy

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下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP131541
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The studied mouse model have a 5BP deletion in the RPGR gene and CRISPR/Cas9-mediated in vivo genome editing therapy was designed to repair it. The next-generation sequencing is done to verify the 5BP correction.The results show homology-directed repair in the target site.
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2018-01-27
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