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NGS on the 5BP correction followed by genome editing therapy

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NIAID Data Ecosystem2026-04-25 收录
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The studied mouse model have a 5BP deletion in the RPGR gene and CRISPR/Cas9-mediated in vivo genome editing therapy was designed to repair it. The next-generation sequencing is done to verify the 5BP correction.The results show homology-directed repair in the target site.

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2018-01-27
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