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Molecular classification of mature aggressive B cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens

NIAID Data Ecosystem2026-03-10 收录

淋巴瘤分子分型

数字基因表达

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48184 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2018-08-10

淋巴瘤分子分型

NF-κB信号通路

MALT lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway. Gastric MALT lymphomas harboring

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DNMT3A mutations define a unique biological and prognostic subgroup associated with cytotoxic T-cells in PTCL-NOS [RNA-Seq]

淋巴瘤分子分型

细胞表观遗传学

Peripheral T-cell lymphomas (PTCLs) are heterogenous T-cell neoplasms often associated with epigenetic dysregulation. We investigated de novo DNA methyltransferase 3A (DNMT3A) mutations in common PTCL

NIAID Data Ecosystem30

Immunohistochemical findings of localized nasal/paranasal DLBCLs.

淋巴瘤分子分型

鼻旁窦DLBCLs

EBER, Epstein–Barr virus-encoded small RNA; GCB, germinal center B-cell; FOXP1, forehead box protein 1; GCET1; germinal center B-cell expressed transcript 1.

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Copy number abnormality, MYC activity and the genetic fingerprint of normal B-cells and the microRNA profile of DLBCL-77. Homo sapiens

淋巴瘤分子分型

miRNA表达谱分析

A better understanding of the pathogenesis of diffuse large B-cell lymphoma (DLBCL) has clarified its relationship to normal B-cells, pointed to distinct mechanisms of cell transformation, and facilit

NIAID Data Ecosystem30

Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy. Expression of TCF3 target genes defines a subclass of diffuse large B-cell lymphoma characterized by up-regulation of MYC target genes and poor clinical outcome following R-CHOP therapy

淋巴瘤分子分型

肿瘤预后生物标志物

Fifty-eight retrospectively-ascertained local cases of diffuse large B-cell lymphoma (DLBCL) were segregated into two large subgroups with divergent overall survival through expression profiling of 13

NIAID Data Ecosystem20

Molecular classification of mature aggressive B cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens

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