PPARG
收藏rgd.mcw.edu2025-03-23 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=14042986
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ENCODES a protein that exhibits nuclear receptor activity; alpha-actinin binding (ortholog); arachidonate binding (ortholog); INVOLVED IN negative regulation of gene expression; positive regulation of cholesterol efflux; positive regulation of DNA-templated transcription; PARTICIPATES IN DNA modification pathway; Wnt signaling, non-canonical pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN nucleus; cytosol (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 1,3-thiazolidine-2,4-dione; arotinoid acid; Bisphenol A diglycidyl ether
编码一种表现出核受体活性的蛋白质;α-肌动蛋白结合(同源);花生四烯酸结合(同源);参与基因表达的负向调控;正向调控胆固醇外排;正向调控DNA模板转录;参与DNA修饰途径;参与Wnt信号通路,非典型途径;与腹部肥胖-代谢综合征(同源)相关;急性肾衰竭(同源);急性肺损伤(同源);存在于细胞核;细胞质(同源);细胞质核周区(同源);与1,3-噻唑烷-2,4-二酮;阿罗尼酸;双酚A二缩水甘油醚相互作用。
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