RNA high-throughput sequencing in synovium of human temporomandibular joint osteoarthritis.

To investigate differentially expressed lncRNAs,circRNAs,miRNAs and mRNAs in synovium of human temporomandibular joint osteoarthritis (TMJOA), we performed RNA high-throughput sequencing in synovium of human TMJOA. We then performed gene expression profiling analysis using data obtained from RNA-seq . Patients with reducible anterior disc displacement were used as control groups and patients with TMJOA were used as experimental group.