Asymmetric Synthesis of Sulfinamides Using (−)-Quinine as Chiral Auxiliary
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A process has been designed and demonstrated for the asymmetric synthesis of sulfinamides using quinine as auxiliary. A variety of chiral sulfinamides including N-alkyl sulfinamides with diverse structure were prepared in good yields and excellent enantioselectivity starting from easily available and inexpensive reagents. The auxiliary quinine could be recovered and recycled.
创建时间:
2016-02-22



