Data underlying the research on particle manipulation using hydrodynamic forcing. This dataset consist of the experimental data of two particles coming close to each other in a Hele-Shaw cell.

The reseach objective is to present a microfluidic approach to achieve the dynamic control of particle pathlines within a flow through microfluidic device. Our approach combines three key aspects: the design of a flow-through microfluidic flow cell with the ability to manipulate the streamlines of the flow, an optimization procedure to find a priori optimal particle path-lines, and a Proportion-Integral-Derivative-based (PID) feedback controller to provide real time control over the particle manipulations. The experimental raw images were recorded with a sCMOS camera (PCO) with a pixel pitch of 6.5 μm. The camera was mounted on a microscope (Nikon Eclipse Ti) with a 1x objective. The acquisition frequency was 5 Hz corresponding to an average in-plane displacement of 4-6 pixels between two consecutive recordings. The zip file contains the raw images and the MATLAB script used to do an experiment of two particles coming close to each other by only using the hydrodynamic forcing in a Hele-Shaw cell.

本研究旨在提出一种微流控方法，以实现微流控器件内流体流动中颗粒流迹的动态调控。本方案整合三大核心维度：其一，设计可调控流场流线的直流通微流控流池；其二，构建用于先验优化颗粒流迹的优化流程；其三，采用基于比例-积分-微分（Proportion-Integral-Derivative, PID）的反馈控制器，实现对颗粒调控过程的实时控制。实验原始图像由sCMOS相机（PCO）采集，该相机像素间距为6.5 μm。相机搭载于搭配1×物镜的尼康（Nikon）Eclipse Ti显微镜上。采集频率为5 Hz，对应两次连续采集之间的平面内平均位移为4至6像素。本压缩包包含实验原始图像与MATLAB脚本，该脚本用于实现仅通过海勒-肖（Hele-Shaw）池内的流体动力驱动，使两颗颗粒相互靠近的实验。