Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
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Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers
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创建时间:
2013-01-02
相关数据集
Additional file 6 of ASXL3 bridges BRD4 to BAP1 complex and governs enhancer activity in small cell lung cancer
Additional file 6: Table S5. Super enhancers that are co-occupied by both ASXL3 and BRD4.
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FOXA2 suppresses endometrial carcinogenesis and epithelial-mesenchymal transition by regulating enhancer activity
FOXA2 encodes a transcription factor mutated in 10% of endometrial cancers (ECs), with a higher mutation rate in aggressive variants. FOXA2 has essential roles in embryonic and uterine development. Ho
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Adenovirus small E1A directs activation of Alu transcription at YAP/TEAD- and AP-1- bound enhancers through interactions with the EP400 chromatin remodeler [RNA-Seq]. Adenovirus small E1A directs activation of Alu transcription at YAP/TEAD- and AP-1- bound enhancers through interactions with the EP400 chromatin remodeler [RNA-Seq]
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PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]. PHF13 Activates Enhancers to Promote TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq]
We investigated the role of PHF13 in TGFβ-induced Epithelial-to-Mesenchymal Transition and found PHF13 is essential for TGFβ-promoted broadest H3K4me3 domains and super-enhancers activation. Overall d
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Additional file 3 of A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease
Additional file 3. Comparison of enhancer-gene pairs with TADs and EPUs.
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