Risk that an infant in the placebo group would fail to achieve high scores on tests of language, cognitive and motor skill development1.

1 High scores were defined as those scores achieved by the highest performing infants whereby n had the lowest possible deviation from 25% of all infants, by sex. Odds ratios and 5th-95th confidence interval (CI) determined using contingency tables with P values determined using Fisher exact analysis.2 CDI, MacArthur Communicative Development Inventory.3 BSID, Bayley Scales of Infant Development III.