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Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY Descriptor: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION Authors: Rudolph, M.G. Deposit date: 2019-12-13 Release date: 2020-02-12 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.04 Å) Cite: Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020

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2019-12-13
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