Remineralizing Enamel : A Literature Review

Background: Tooth enamel is a non-living tissue, once matured it can no longer remineralization itself. Unfortunately, there are only a few studies that analyze the risks and benefits in applications towards remineralization. The objective was to examine the effectiveness and risks of synthetic applications towards remineralizing tooth enamel.
Methods: Experimental trials focusing on the effect of synthetic applications on tooth enamel such as, surface hardness, surface thickness and overall effectiveness were included in this review. Published articles from 1978 to 2018 were identified using specific keywords terms in the ScienceDirect and PubMed database. Each study was independently screened to meet eligibility and asses risk of bias, if any.
Results: Seven experimental reports applying three synthetic methods: Ca/PI ratios of stimulated saliva, Nano-hydroxyapatite and Calcarea Fluorica tablets were evaluated. Application process and outcomes varied throughout each study. Ca/PI rat...