Stimulating effect of a new triterpene derived from <i>Anoectochilus elwesii</i> on glucose uptake in insulin-resistant human HepG2 cells
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A new triterpene (<b>1</b>), 3-β-<i>O</i>-olean-11,13 (18)-diene-23,28-dioic acid, together with five known compounds (<b>2</b>–<b>6</b>), was isolated from <i>Anoectochilus elwesii</i> and their structures were elucidated by extensive spectroscopic methods and comparison with the literature data. Compound <b>1</b> was the first example of highly oxygenated triterpene obtained from <i>Anoectochilus</i> genus. The isolated compounds were evaluated on insulin-resistant human HepG2 cells for stimulating glucose uptake activity and the new compound displayed highly potent effect on the stimulation of glucose uptake in human HepG2 cells.
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Taylor & Francis创建时间：
2016-01-19
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